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SCIENTIFIC EVIDENCE

The latest publications about the Cube Navigation System

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Periradicular infiltration of the L5 route requiring a double-angulated route due to degenerative changes.  The Cube Navigation System was used to simplify access to the target, even though the entry route was extremely angulated. The target was hit on the first try.

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Krammer, L., Hostettler, R., Wetzel, S.

Journal of Vascular and Interventional Radiology, 2023

Phantom study evaluating accuracy and efficiency of the Access Cube as compared to the standard of care Free Hand Method.  Statistically significantly improved accuracy and overall lower intervention time.

Kidney Ablation using the Cube Navigation System

Microwave ablation of a borderline-sized renal cell carcinoma on a solitary kidney in an inoperable patient. The Access Cube was used in this challenging procedure, supporting accurate needle placement.

A radiologist performing a bone biopsy using the Cube Navigation System

First case study performed with the Access Cube: a pelvic bone biopsy utilizing the navigation and needle holding capacity of the CNS. Johanniter-Krankenhaus and Waldkrankenhaus in Bonn, Germany.

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A suspected infection on the edge of a resected liver was reached on the first try, despite a challenging, double-angulated entry route.  Drainage performed at the University Clinic in Jena, Germany.

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Biopsy of a thoracic mass using the Access Cube to support planning of an optimal route which would not damage surrounding tissue. 

Biopsy was diagnostic and performed without complication.

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A lung biopsy performed with the Puncture Cube, at the Istituto Nazionale Tumori in Naples, Italy.  After less than 30 minutes of training, the team successfully used the Cube Navigation System to reach the biopsy target.

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Diepers M., Gruber P.,  Remonda L., et. al.

Frontiers in Surgery, 2023

Case series to report experience with the patient-mounted Cube Navigation System to guide needle placement for complex access routes in lumbar pain therapy. 

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An extremely angulated, dual-oblique route to the liver made easy with the Access Cube.  Microwave ablation on a patient with hemochromatosis and singular HCC performed at Klinik Hirslanden, Zurich, Switzerland.

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Krammer, L., Kadrijaj, V., Hostettler, R., et al.

CIRSE, 2022

Poster Presentation. First evaluation of accuracy and efficiency of the Access Cube as compared to the standard of care Free Hand Method.  Statistically significantly improved accuracy and overall lower intervention time. The number of CT scans was reduced to 1.4 versus FHM 2.8.

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Grigoriadis, S.; Filippiadis, D.; Stamatopoulou, V. et al.

Medicina, 2022

Five clinical cases of splanchnic nerve radiofrequency neurolysis were performed using the Cube Navigation System.  The Puncture Cube was found to be simple to use, while allowing for highly accurate needle placement and optimal calculation of double oblique access routes.

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Mokry, A., Willmitzer, F., Hostettler, R. et al.

Neuroradiology, 2019

Assessment of the Puncture Cube as compared to the standard of care Free Hand Method.  Accuracy and time requirements were compared in this ex-vivo, phantom study. 

Puncture Cube resulted in a statistically significantly improved accuracy and overall lower intervention time. Number of CT scans was reduced to 2.3 versus FHM 2.8.

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Scharll, Y., Mitteregger, A., Lamier, G. et al.

Journal of Clinical Medicine, 2022

Assessment of the Puncture Cube as compared to a robotic navigation device.
Puncture Cube was found to be competitive with other navigational systems on the market as well as having 30% faster procedure time, not including set up or breakdown time

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